14. "Canada Domestic Substances List (DSL)","Canada Toxicological Index Service - Workplace Hazardous Materials Information System - WHMIS (English)","Canada Toxicological Index Service - Workplace Hazardous Materials Information System - WHMIS (French)","IMO IBC Code Chapter 18: List of products to which the Code does not apply","OECD Representative List of High Production Volume (HPV) Chemicals","US - Pennsylvania - Hazardous Substance List","US DOE Temporary Emergency Exposure Limits (TEELs)","US NFPA 30B Manufacture and Storage of Aerosol Products - Chemical Heat of Combustion","US Toxic Substances Control Act (TSCA) - Inventory","US TSCA Section 8 (a) Inventory Update Rule (IUR) - Partial Exemptions" Section 16 - OTHER INFORMATION LIMITED EVIDENCE ■ Contact with air may produce sufficient heat to ignite combustible materials.*. ■ Cumulative effects may result following exposure*. ■ Limited evidence of a carcinogenic effect*. * (limited evidence). Reasonable care has been taken in the preparation of this information, but the author makes no warranty of merchantability or any other warranty, expressed or implied, with respect to this information. The author makes no representations and assumes no liability for any direct, incidental or consequential damages resulting from its use. For additional technical information please call our toxicology department on +800 CHEMCALL. ■ Classification of the mixture and its individual components has drawn on official and authoritative sources as well as independent review by the Chemwatch Classification committee using available literature references. A list of reference resources used to assist the committee may be found at: www.chemwatch.net/references. ■ The (M)SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. Many factors determine whether the reported Hazards are Risks in the workplace or other settings. Risks may be determined by reference to Exposures Scenarios. Scale of use, frequency of use and current or available engineering controls must be considered. This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission from CHEMWATCH. TEL (+61 3) 9572 4700. Issue Date: Sep-24 -2008 Print Date:Apr-22 -2010
1. Material Safety Data Sheet Hydrogen Peroxide sc-203336 Hazard Alert Code Key: EXTREME HIGH MODERATE LOW Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME Hydrogen Peroxide STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. NFPA SUPPLIER Company: Santa Cruz Biotechnology, Inc. Address: 2145 Delaware Ave Santa Cruz, CA 95060 Telephone: 800.457.3801 or 831.457.3800 Emergency Tel: CHEMWATCH: From within the US and Canada: 877-715-9305 Emergency Tel: From outside the US and Canada: +800 2436 2255 (1-800-CHEMCALL) or call +613 9573 3112 PRODUCT USE At varying concentrations used for bleaching and deodourizing of textiles, wood pulp, hair, fur etc.; source of organic and inorganic peroxides; pulp and paper industry; plasticizers; rocket fuel; foam rubber. Manufacture of glycerol; antichlor; dyeing; electroplating; antiseptic, laboratory reagent, epoxidation, hydroxylation, oxidation and reduction; viscosity control for starch and cellulose derivatives; refining and cleaning metals; bleaching and oxidizing agent in food; neutralizing agent in wine distillation; seed disinfectant; substitute for chlorine water and sewage treatment. SYNONYMS H2-O2, albone, Hioxyl, "hydrogen peroxide, solution (over 52% peroxide)", "hydrogen peroxide, stabilized (over 60% peroxide)", inhibine, oxydol, perhydrol, perone, peroxan, peroxide, superoxol, T -stuff Section 2 - HAZARDS IDENTIFICATION CANADIAN WHMIS SYMBOLS EMERGENCY OVERVIEW RISK Heating may cause an explosion. Causes severe burns. Risk of serious damage to eyes. Harmful by inhalation and if swallowed. POTENTIAL HEALTH EFFECTS ACUTE HEALTH EFFECTS FLAMMABILITY 0 HEALTH HAZARD 3 INSTABILITY 1 OX
4. distension due to gas formation" Fisher Scientific MSDS. Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of lung edema often do not manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her should be considered. (ICSC24419/24421. Section 5 - FIRE FIGHTING MEASURES Vapor Pressure (mmHg): 5.025 @ 30C Upper Explosive Limit (%): Not applicable Specific Gravity (water=1): 1.40 @ 25C Lower Explosive Limit (%): Not applicable EXTINGUISHING MEDIA ■ For hydrogen peroxide NOTE: Chemical extinguishing agents may accelerate decomposition. [CCINFO]. FOR SMALL FIRE: USE FLOODING QUANTITIES OF WATER. DO NOT use dry chemicals, CO2 or foam. FOR LARGE FIRE: Flood fire area with water from a protected position. FIRE FIGHTING ■ Use water delivered as a fine spray to control fire and cool adjacent area. DO NOT approach containers suspected to be hot. Cool fire exposed containers with water spray from a protected location. If safe to do so, remove containers from path of fire. Equipment should be thoroughly decontaminated after use. GENERAL FIRE HAZARDS/HAZARDOUS COMBUSTIBLE PRODUCTS ■ Will not burn but increases intensity of fire. Heating may cause expansion or decomposition leading to violent rupture of containers. Heat affected containers remain hazardous. Contact with combustibles such as wood, paper, oil or finely divided metal may cause ignition, combustion or violent decomposition. May emit irritating, poisonous or corrosive fumes. FIRE INCOMPATIBILITY ■ Avoid storage with reducing agents. Avoid any contamination of this material as it is very reactive and any contamination is potentially hazardous PERSONAL PROTECTION Glasses: Full face- shield. Gloves: 1.NAT+NEOPR+NITRILE 2.NEOPRENE Respirator: Type B Filter of sufficient capacity Section 6 - ACCIDENTAL RELEASE MEASURES MINOR SPILLS ■ Clean up all spills immediately. No smoking, naked lights, ignition sources. Avoid all contact with any organic matter including fuel, solvents, sawdust, paper or cloth and other incompatible materials; as ignition may result. Avoid breathing dust or vapors and all contact with skin and eyes. Control personal contact by using protective equipment. Contain and absorb spill with dry sand, earth, inert material or vermiculite DO NOT use sawdust as fire may result. Scoop up solid residues and seal in labeled drums for disposal. Neutralize/decontaminate area. MAJOR SPILLS ■ Clear area of personnel and move upwind. Alert Emergency Responders and tell them location and nature of hazard. May be violently or explosively reactive. Wear full body protective clothing with breathing apparatus. Prevent, by any means available, spillage from entering drains or water course. Consider evacuation. No smoking, flames or ignition sources. Increase ventilation. Contain spill with sand, earth or other clean, inert materials. NEVER use organic absorbents such as sawdust, paper, cloth; as fire may result. Avoid any contamination by organic matter.
10. peroxide is a transient material (requires stabilization). Miscible in water, soluble in ether, insoluble in petroleum ether and decomposed by many organic solvents. Carried as an aqueous solution. Section 10 - CHEMICAL STABILITY CONDITIONS CONTRIBUTING TO INSTABILITY ■ Presence of incompatible materials. Product is considered stable under normal handling conditions. Prolonged exposure to heat. Hazardous polymerization will not occur. Solutions of hydrogen peroxide slowly decompose, releasing oxygen, and so are often stabilised by the addition of acetanilide, etc. STORAGE INCOMPATIBILITY ■ Hydrogen peroxide is a powerful oxidiser contamination or heat may cause self accelerating exothermic decomposition with oxygen gas and steam release - this may generate dangerous pressures - steam explosion. reacts dangerously with rust, dust, dirt, iron, copper, acids, metals and salts, organic material. is unstable if heated. (e.g): one volume of 70% hydrogen peroxide solution decomposes to produce 300 volumes of oxygen gas. in presence of a strong initiating source may be explosively reactive concentrated or pure material can generate heat and decompose spontaneously; can ignite or explode when heated, shocked, contaminated; or if placed in a basic (>7) environment, especially in the presence of metal ions mixtures with combustible materials may result in spontaneous combustion or may be impact- or heat- sensitive - evaporation or drying on towels or mop may cause a fire. reacts violently with reducing agents, alcohols, ammonia, carboxylic acids, acetic acid, cobalt oxides, copper(II) chloride, ethers, metal powder, permanganates, acetone, benzenesulfonic anhydride, 1,1-dimethylhydrazine, dimethylphenylphosphine, gadolinium hydroxide, hydrogen selenide, iron oxides, lithium tetrahydroaluminate, magnesium tetrahydroaluminate, manganese(II) oxide, mercury oxide, methyl hydrazine, nickel monoxide, nitrogenous bases, osmium tetraoxide, alpha-phenylselenoketones, phosphorus, phosphorus(V) oxide, quinoline, tetrahydrothiophene, tin(II) chloride, thiodiglycol, thiophane, tin(II) chloride, unsaturated organic compounds, readily oxidisable and combustible materials; avoid contact with combustibles including lubricants and graphite reacts with cobalt, copper and its alloys, chromium, iridium, iron, lead, manganese, Monel, osmium, palladium, platinum, gold, silver, zinc, and other catalytic metals, metal oxides and salts - avoid metallic bowls and stirrers. violent catalytic decomposition will occur in contact with certain metals such as iron, copper, chromium, brass, bronze, lead, silver, manganese or their salts. forms unstable and possible explosive materials with acetic anhydride, aconitic acid, aniline, carboxylic acids, 1,4- diazabicyclo[2,2,2]octane, diphenyl diselenide, ethyl acetate, glycols, ketene, ketones, triethyltin hydroperoxide, 1,3,5- trioxane, vinyl acetate. is incompatible with mercurous chloride decomposes in presence of alkalis and even ordinary dust or rust decomposes slowly at ordinary temperatures and builds up pressure in a closed container; the rate of decomposition doubles for each 10 deg C rise in temperature and decomposition becomes self-sustaining at 141 deg. C contact with rough surfaces can cause decomposition attacks and may ignite some plastics, rubber and coatings Inorganic reducing agents react with oxidizing agents to generate heat and products that may be flammable, combustible, or otherwise reactive. Their reactions with oxidizing agents may be violent. Incidents involving interaction of active oxidants and reducing agents, either by design or accident, are usually very energetic and examples of so-called redox reactions. Avoid any contamination of this material as it is very reactive and any contamination is potentially hazardous Inorganic oxidising agents can react with reducing agents to generate heat and products that may be gaseous (causing pressurization of closed containers). The products may themselves be capable of further reactions (such as combustion in the air). Organic compounds in general have some reducing power and can in principle react with compounds in this class. Actual reactivity varies greatly with the identity of the organic compound. Inorganic oxidising agents can react violently with active metals, cyanides, esters, and thiocyanates. Avoid strong bases. Avoid storage with reducing agents. For incompatible materials - refer to Section 7 - Handling and Storage. Section 11 - TOXICOLOGICAL INFORMATION hydrogen peroxide TOXICITY AND IRRITATION ■ unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances. TOXICITY IRRITATION Dermal (rabbit) LD50: 4060 mg/kg Nil Reported Dermal (rabbit) LDLo: 500 mg/kg Inhalation (mouse) LC50: 2000 mg/kg/4h ■ Asthma-like symptoms may continue for months or even years after exposure to the material ceases. This may be due to a non-allergenic condition known as reactive airways dysfunction syndrome (RADS) which can occur following exposure to high levels of highly irritating compound. Key criteria for the diagnosis of RADS include the absence of preceding respiratory disease, in a non-atopic individual, with abrupt onset of persistent asthma-like symptoms within minutes to hours of a documented exposure to the irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to severe
11. bronchial hyperreactivity on methacholine challenge testing and the lack of minimal lymphocytic inflammation, without eosinophilia, have also been included in the criteria for diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an infrequent disorder with rates related to the concentration of and duration of exposure to the irritating substance. Industrial bronchitis, on the other hand, is a disorder that occurs as result of exposure due to high concentrations of irritating substance (often particulate in nature) and is completely reversible after exposure ceases. The disorder is characterised by dyspnea, cough and mucus production. For hydrogen peroxide: Hazard increases with peroxide concentration, high concentrations contain an additive stabiliser. Pharmacokinetics Hydrogen peroxide is a normal product of metabolism. It is readily decomposed by catalase in normal cells. In experimental animals exposed to hydrogen peroxide, target organs affected include the lungs, intestine, thymus, liver, and kidney, suggesting its distribution to those sites. Hydrogen peroxide has been detected in breath. Absorption: Hydrogen peroxide is decomposed in the bowel before absorption . When applied to tissue, solutions of hydrogen peroxide have poor penetrability . Distribution Hydrogen peroxide is produced metabolically in intact cells and tissues. It is formed by reduction of oxygen either directly in a two-electron transfer reaction, often catalysed by flavoproteins, or by an initial one-electron step to O2 followed by dismutation to hydrogen peroxide . Hydrogen peroxide has been detected in serum and in intact liver. based on the results of toxicity studies, the lungs, intestine, thymus, liver, and kidney may be distribution sites. In rabbits and cats that died after intravenous administration of hydrogen peroxide, the lungs were pale and emphysematous . Following intraperitoneal injection of hydrogen peroxide in mice, pyknotic nuclei were induced in the intestine and thymus (IARC 1985). Degeneration of hepatic and renal tubular epithelial tissue was observed following oral administration of hydrogen peroxide to mice . Metabolism Glutathione peroxidase, responsible for decomposing hydrogen peroxide, is present in normal human tissues (IARC 1985). When hydrogen peroxide comes in contact with catalase, an enzyme found in blood and most tissues, it rapidly decomposes into oxygen and water . Excretion Hydrogen peroxide has been detected in human breath at levels ranging from 1.0+/-.5 :g/L to 0.34+/ -0.17 :g/L Carcinogenicity Gastric and duodenal lesions including adenomas, carcinomas, and adenocarcinomas have been observed in mice treated orally with hydrogen peroxide. Marked strain differences in the incidence of tumors have been observed. Papilloma development has been observed in mice treated by dermal application. Genotoxicity Hydrogen peroxide induced DNA damage, sister chromatid exchanges and chromosomal aberrations in mammalian cells in vitro . Hydrogen peroxide induced DNA damage in bacteria (E. coli), and was mutagenic to bacteria (Salmonella typhimurium) and the fungi, Neurospora crassa and Aspergillis chevallieri, but not to Streptomyces griseoflavus. It was not mutagenic to Drosophila melanogaster or to mammalian cells in vitro. Developmental Toxicity Malformations have been observed in chicken embryos treated with hydrogen peroxide, but experiments with mice and rats have been negative. Female rats that received 0.45% hydrogen peroxide (equivalent to approximately 630 mg/kg/day)7 as the sole drinking fluid for five weeks produced normal litters when mated with untreated males. Doses of 1.4 to 11 :mol/egg hydrogen peroxide (purity 30%) dissolved in water were injected into the airspace of groups of 20 - 30 white leghorn chicken eggs on day 3 of incubation. Embryos were examined on day 14. The incidence of embryonic deaths and malformations was dose-related and detected at doses of 2.8 :mol/egg and above. The combined ED50 was 2.7 :mol/egg Reproductive Toxicity A 1% solution of hydrogen peroxide (equivalent to 1900 mg/kg/day) given as the sole drinking fluid to three-month-old male mice for 7-28 days did not cause infertility. The substance is classified by IARC as Group 3: NOT classifiable as to its carcinogenicity to humans. Evidence of carcinogenicity may be inadequate or limited in animal testing. CARCINOGEN Hydrogen peroxide International Agency for Research on Cancer (IARC) - Agents Reviewed by the IARC Monographs Group 3 Hydrogen peroxide US ACGIH Threshold Limit Values (TLV) - Carcinogens Carcinogen Category A3 Section 12 - ECOLOGICAL INFORMATION Refer to data for ingredients, which follows: HYDROGEN PEROXIDE: ■ For hydrogen peroxide: log Kow : -1.36 Environmental fate: Hydrogen peroxide is a naturally occurring substance (typical background concentrations < 1 - 30 g/l). Almost all cells with the exception of anaerobic bacteria produce it in their metabolism. Hydrogen peroxide is a reactive substance in the presence of other substances, elements, radiation, materials and can be degraded by micro-organisms or higher organisms. Air : Hydrogen peroxide may be removed from the atmosphere by photolysis giving rise to hydroxyl radicals, by reaction with hydroxyl radicals, or by heterogenous loss processes such as rain-out. Significantly higher hydrogen peroxide concentrations are found in polluted atmospheres as compared with clean air. These concentrations are believed to arise from photochemically-initiated oxidation of reactive hydrocarbons . Under severe smog conditions, daytime levels of hydrogen peroxide as high as 0.18 ppm have been reported, but atmospheric night-time levels of 2-5 ppb did not correlate to smog intensity Soil: No information was found in the secondary sources searched regarding the transformation or persistence of hydrogen peroxide in soil, however, solutions of hydrogen peroxide gradually deteriorate
12. Water Hydrogen peroxide is a naturally occurring substance. Surface water concentrations of hydrogen peroxide have been found to vary between 51 -231 mg/L, increasing both with exposure to sunlight and the presence of dissolved organic matter Hydrogen peroxide degrades by various mechanisms, including chemical reduction and enzymatic (catalase and peroxidase) decomposition by algae, zooplankton, and bacteria. Microorganisms, especially bacteria, account for the majority of degradation, significantly more than all other chemical and biological mechanisms. The rate at which hydrogen peroxide decomposes in natural water can vary from a few minutes to more than a week, depending on numerous chemical, biological, and physical factors. Hydrogen peroxide is rapidly degraded in a biological waste water treatment plant. Hydrogen peroxide adsorbs poorly to sediment particles and is rapidly degraded, thus accumulation in the sediment is also not expected Hydrogen peroxide (log Kow < -1) is an inorganic substance and therefore shows little potential to bioaccumulate. Ecotoxicity: Fish LC50 (96 h): catfish 37.4 mg/l Fish LC50 (24 h): mackerel 89 mg/l; chameleon gobi 155 mg/l Zebra mussel LC50 (28 h) 30 mg/l; (228 h): 12 mg/l Ecotoxicity data show that microorganisms (i.e., bacteria, algae) and zooplankton present in aquatic ecosystems are generally less tolerant of hydrogen peroxide exposure than are fish or other vertebrates. Effects of short-term exposures on sensitive bacteria and invertebrates (e.g., Daphnia pulex) have been observed at concentrations in the low mg/L (ppm) range, while effects on sensitive algae have been reported at levels less than 1.0 mg/L. Algae are the most sensitive species for hydrogen peroxide. The algal EC50 of hydrogen peroxide was 1.6-5 mg/l, while the NOEC was 0.1 mg/l. In a 21 -d continuous exposure study on Daphnia magna, the chronic no observable effect concentration (NOEC) for reproduction was 0.63 mg/L and the NOEC for mortality was 1.25 mg/L. In chronic toxicity studies with invertebrates (zebra mussels) and hydrogen peroxide shows an NOEC of 2 mg/l. The PNEC of hydrogen peroxide is equal to 10 ug/l - Risk mitigation is needed to ensure that use of hydrogen peroxide will not adversely impact aquatic life. An acute water quality criterion or "benchmark" has been determined. For hydrogen peroxide, the acute benchmark is 0.7 mg/L. This value was calculated using the extensive toxicity database for hydrogen peroxide and procedures in U.S. Environmental Protection Agency guidance for deriving numerical national water quality criteria. The use of hydrogen peroxide in intensive aquaculture in finfish (at up to 100 mg/L for 60 minutes) and finfish eggs (at up to 1,000 mg/L for 15 minutes) is not expected to have a significant impact on the environment. ■ DO NOT discharge into sewer or waterways. WATER: Ecotoxicity Ingredient Persistence: Water/Soil Persistence: Air Bioaccumulation Mobility hydrogen peroxide LOW LOW HIGH water LOW LOW HIGH Section 13 - DISPOSAL CONSIDERATIONS US EPA Waste Number & Descriptions A. General Product Information Ignitability characteristic: use EPA hazardous waste number D001 (waste code I) Corrosivity characteristic: use EPA hazardous waste number D002 (waste code C) Disposal Instructions All waste must be handled in accordance with local, state and federal regulations. ¦ Puncture containers to prevent re-use and bury at an authorized landfill. Legislation addressing waste disposal requirements may differ by country, state and/ or territory. Each user must refer to laws operating in their area. In some areas, certain wastes must be tracked. A Hierarchy of Controls seems to be common - the user should investigate: Reduction, Reuse Recycling Disposal (if all else fails) This material may be recycled if unused, or if it has not been contaminated so as to make it unsuitable for its intended use. If it has been contaminated, it may be possible to reclaim the product by filtration, distillation or some other means. Shelf life considerations should also be applied in making decisions of this type. Note that properties of a material may change in use, and recycling or reuse may not always be appropriate. DO NOT allow wash water from cleaning equipment to enter drains. Collect all wash water for treatment before disposal. For small quantities of oxidizing agent: Cautiously acidify a 3% solution to pH 2 with sulfuric acid. Gradually add a 50% excess of sodium bisulfite solution with stirring. Add a further 10% sodium bisulfite. If no further reaction occurs (as indicated by a rise in temperature) cautiously add more acid. Recycle wherever possible. Consult manufacturer for recycling options or consult Waste Management Authority for disposal if no suitable treatment or disposal facility can be identified. Treat and neutralize at an approved treatment plant. Treatment should involve: Neutralization followed by: Burial in a licensed land-fill or Incineration in a licensed apparatus (after admixture with suitable combustible material) Decontaminate empty containers. Observe all label safeguards until containers are cleaned and destroyed. Section 14 - TRANSPORTATION INFORMATION
5. Use spark-free and explosion-proof equipment. Collect any recoverable product into labeled containers for possible recycling. DO NOT mix fresh with recovered material. Collect residues and seal in labeled drums for disposal. Wash area and prevent runoff into drains. Decontaminate equipment and launder all protective clothing before storage and re-use. If contamination of drains or waterways occurs advise emergency services. For hydrogen peroxide: Dilute with large quantities of water (at least ten (10) times the volume of hydrogen peroxide). Sodium bicarbonate may be used to accelerate breakdown. PROTECTIVE ACTIONS FOR SPILL From IERG (Canada/Australia) Isolation Distance 25 meters Downwind Protection Distance 100 meters FOOTNOTES 1 PROTECTIVE ACTION ZONE is defined as the area in which people are at risk of harmful exposure. This zone assumes that random changes in wind direction confines the vapour plume to an area within 30 degrees on either side of the predominant wind direction, resulting in a crosswind protective action distance equal to the downwind protective action distance. 2 PROTECTIVE ACTIONS should be initiated to the extent possible, beginning with those closest to the spill and working away from the site in the downwind direction. Within the protective action zone a level of vapour concentration may exist resulting in nearly all unprotected persons becoming incapacitated and unable to take protective action and/or incurring serious or irreversible health effects. 3 INITIAL ISOLATION ZONE is determined as an area, including upwind of the incident, within which a high probability of localised wind reversal may expose nearly all persons without appropriate protection to life -threatening concentrations of the material. 4 SMALL SPILLS involve a leaking package of 200 litres (55 US gallons) or less, such as a drum (jerrican or box with inner containers). Larger packages leaking less than 200 litres and compressed gas leaking from a small cylinder are also considered "small spills". LARGE SPILLS involve many small leaking packages or a leaking package of greater than 200 litres, such as a cargo tank, portable tank or a "one -tonne" compressed gas cylinder. 5 Guide 143 is taken from the US DOT emergency response guide book. 6 IERG information is derived from CANUTEC - Transport Canada. ACUTE EXPOSURE GUIDELINE LEVELS (AEGL) (in ppm) AEGL 1: The airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic nonsensory effects. However, the effects are not disabling and are transient and reversible upon cessation of exposure. AEGL 2: The airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting adverse health effects or an impaired ability to escape. AEGL 3: The airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening health effects or death. EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG) The maximum airborne concentration below which it is believed that nearly all individuals could be exposed for up to one hour WITHOUT experiencing or developing life-threatening health effects is: hydrogen peroxide 100ppm irreversible or other serious effects or symptoms which could impair an individual's ability to take protective action is: hydrogen peroxide 50ppm other than mild, transient adverse effects without perceiving a clearly defined odour is: hydrogen peroxide 10ppm American Industrial Hygiene Association (AIHA) Ingredients considered according exceed the following cutoffs Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0% R50 >= 0.25% Corrosive (C) >= 5.0% R51 >= 2.5% else >= 10% where percentage is percentage of ingredient found in the mixture
3. conjunctiva. Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS HAZARD RATINGS Min Max Flammability: 0 Toxicity: 2 Body Contact: 4 Reactivity: 3 Chronic: 2 Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 NAME CAS RN % hydrogen peroxide 7722-84 -1 >90 (as H2O2 in solution) proprietary stabilizer as Not spec acetanilide, sodium stannate etc. water 7732-18 -5 Section 4 - FIRST AID MEASURES SWALLOWED ■ For advice, contact a Poisons Information Center or a doctor at once. Urgent hospital treatment is likely to be needed. If swallowed do NOT induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent aspiration. Observe the patient carefully. Never give liquid to a person showing signs of being sleepy or with reduced awareness; i.e. becoming unconscious. Give water to rinse out mouth, then provide liquid slowly and as much as casualty can comfortably drink. Transport to hospital or doctor without delay. EYE ■ If this product comes in contact with the eyes: Immediately hold eyelids apart and flush the eye continuously with running water. Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids. Continue flushing until advised to stop by the Poisons Information Center or a doctor, or for at least 15 minutes. Transport to hospital or doctor without delay. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. SKIN ■ If skin or hair contact occurs: Immediately flush body and clothes with large amounts of water, using safety shower if available. Quickly remove all contaminated clothing, including footwear. Wash skin and hair with running water. Continue flushing with water until advised to stop by the Poisons Information Center. Transport to hospital, or doctor. INHALED ■ If fumes or combustion products are inhaled remove from contaminated area. Lay patient down. Keep warm and rested. Prostheses such as false teeth, which may block airway, should be removed, where possible, prior to initiating first aid procedures. Apply artificial respiration if not breathing, preferably with a demand valve resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary. Transport to hospital, or doctor. Inhalation of vapors or aerosols (mists, fumes) may cause lung edema. Corrosive substances may cause lung damage (e.g. lung edema, fluid in the lungs). As this reaction may be delayed up to 24 hours after exposure, affected individuals need complete rest (preferably in semi -recumbent posture) and must be kept under medical observation even if no symptoms are (yet) manifested. Before any such manifestation, the administration of a spray containing a dexamethasone derivative or beclomethasone derivative may be considered. This must definitely be left to a doctor or person authorized by him/her. (ICSC13719). NOTES TO PHYSICIAN ■ Hydrogen peroxide at moderate concentrations (5% or more) is a strong oxidant. Direct contact with the eye is likely to cause corneal damage especially if not washed immediately. Careful ophthalmologic evaluation is recommended and the possibility of local corticosteroid therapy should be considered. Because of the likelihood of systemic effects attempts at evacuating the stomach via emesis induction or gastric lavage should be avoided. There is remote possibility, however, that a nasogastric or orogastric tube may be required for the reduction of severe
2. SWALLOWED ■ Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual. ■ The material can produce severe chemical burns within the oral cavity and gastrointestinal tract following ingestion. ■ Hydrogen peroxide may cause blistering and bleeding from the throat and stomach. Ingested hydrogen peroxide may evolve large quantities of oxygen which could hyper -distend the gastro-intestinal tract and may cause internal bleeding Ingestion of large amounts of hydrogen peroxide causes chest and stomach pain, loss of consciousness, and motor disorders in humans and has caused mortality in experimental animals. Ingestion of hydrogen peroxide containing/ generating materials may cause nausea, vomiting and, possibly, internal bleeding. Rapid evolution of oxygen in the acid environment of the stomach (up to 10 times the volume of the ingested solution) may result in severe organ damage. Large doses are presumed to produce gastritis and oesophagitis. Cases of rupture of the colon, proctitis and ulcerative colitis have been reported following hydrogen peroxide enemas. Powders and tablets that generate hydrogen peroxide, such as Oxone (KHSO5), have caused oral and oesophageal burns when ingested. Large amounts of hydrogen peroxide taken orally by humans has caused apnea, dizziness, headache, tremors weakness or numbness in the extremities, convulsions, loss of consciousness and shock. Hydrogen peroxide concentrate is caustic and should not be tasted undiluted. Rats receiving 2.5% hydrogen peroxide (equivalent to approximately 3.5 g/kg/day ) in their drinking water died within 43 days. Cases of rupture of the colon, inflammation of the anus or rectum, and ulcerative colitis have been reported following hydrogen peroxide enemas In five persons who accidentally drank about 50 mL of a 33% hydrogen peroxide solution, symptoms included stomach and chest pain, retention of breath, foaming at the mouth, and loss of consciousness. Later, motor and sensory disorders, fever, microhaemorrhages and moderate leucocytosis were noted. All recovered completely within 2-3 weeks. EYE ■ The material can produce severe chemical burns to the eye following direct contact. Vapors or mists may be extremely irritating. ■ If applied to the eyes, this material causes severe eye damage. ■ Corneal ulcerations due to hydrogen peroxide exposure may not appear for up to a week after exposure; concentrations above 10% are corrosive to the eye. SKIN ■ The material can produce severe chemical burns following direct contactwith the skin. ■ Skin contact is not thought to produce harmful health effects (as classified using animal models). Systemic harm, however, has been identified following exposure of animals by at least one other route and the material may still produce health damage following entry through wounds, lesions or abrasions. Good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting. ■ Skin contact will result in rapid drying, bleaching, leading to chemicalburns on prolonged contact. ■ Open cuts, abraded or irritated skin should not be exposed to this material. ■ Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected. ■ Hydrogen peroxide as a topical gel is used to cleanse minor wounds or minor gum inflammation. In appropriate solution, hydrogen peroxide is used in topical and dental gels Skin contact may cause bleaching, blistering and reddening. Short term contact results in temporary whitening and a tingling sensation due to diffusion of hydrogen peroxide into the skin. The characteristic whitening of the skin occurs after topical application of hydrogen peroxide (1-30%), which is believed the result of avascularity of the skin produced by oxygen bubbles acting microembolically in the capillaries. Concentrations above 50% are corrosive to skin. INHALED ■ If inhaled, this material can irritate the throat andlungs of some persons. ■ Inhalation of vapors or aerosols (mists, fumes), generated by the material during the course of normal handling, may be harmful. ■ Inhalation of quantities of liquid mist may be extremely hazardous, even lethal due to spasm, extreme irritation of larynx and bronchi, chemical pneumonitis and pulmonary edema. ■ Inhalation of excessive levels of mist may result in headache, dizziness, vomiting, diarrhoea, irritability, insomnia and in extreme pulmonary oedema. Systemic poisoning due to hydrogen peroxide inhalation may cause tremors and numbness of the extremities, convulsions, pulmonary oedema, coma and shock. Hydrogen peroxide has poor warning properties. High concentrations of the vapour or mist are likely to cause extreme irritation of the nose and chest, cough, discomfort, shortness of breathe, and inflammation of the nose and throat. CHRONIC HEALTH EFFECTS ■ There has been some concern that this material can cause cancer or mutations but there is not enough data to make an assessment. Limited evidence suggests that repeated or long-term occupational exposure may produce cumulative health effects involving organs or biochemical systems. Hydrogen peroxide as a human food additive is generally regarded as safe when used in certain limitations. In experimental animals, oral administration of hydrogen peroxide causes dental, liver, kidney, stomach, and intestinal damage. Inhalation exposure to hydrogen peroxide caused skin irritation and sneezing in dogs, and high mortality in mice. Hydrogen peroxide added to food is affirmed to be generally regarded as safe (GRAS) by the U.S. FDA when used to treat certain foods in specified limitations [FDA 21 CFR 184.1366 (4/1/93)]. Hydrogen peroxide may be used as a component of articles for use in packaging, handling, transporting, or holding food in accordance with prescribed conditions [FDA 21 CFR 175.105 (4/1/93)]. Dose-related growth retardation, induction of dental caries, and pathological changes in the periodontium were observed in young male rats receiving 1.5% hydrogen peroxide as their drinking fluid (equivalent to approximately 2.1 g/kg/day)2 for 8 weeks . Effects observed in mice treated for 35 weeks with 0.15% hydrogen peroxide as their drinking fluid (equivalent to approximately 0.29 g/kg/day)3 included degeneration of hepatic and renal tubular epithelial tissues, necrosis, inflammation, irregularities of tissue structure of the stomach wall, and hypertrophy of the small intestine wall. Concentrations in excess of 1% (equivalent to approximately 1.9 g/kg/day)4 resulted in pronounced weight loss and death within two weeks. In a sequential study of mice treated with 0.4% hydrogen peroxide in drinking water (equivalent to approximately 0.76 g/kg/day)5 , gastric erosion was observed at 30 days and was present consistently throughout the 108 week study period. Dogs exposed 6 hours/day, 5 days/week for 6 months at an average vapour concentration of 7 ppm (9.73 mg/3 ) of 90% hydrogen peroxide, developed skin irritation, sneezing, lacrimation, and bleaching of the hair. Autopsy disclosed pulmonary irritation and greatly thickened skin, but no hair follicle destruction. No significant changes in blood or urinary parameters were observed . Following eight 6-hour exposures to hydrogen peroxide at a concentration of 79 mg/m3 (56.88 ppm), 7/9 mice died. Following exposure to hydrogen peroxide at 93 mg/m3 , 6 hours/day, 5 days/week for 30 exposures, 1/10 rats died. Repeated or prolonged exposure to acids may result in the erosion of teeth, swelling and or ulceration of mouth lining. Irritation of airways to lung, with cough, and inflammation of lung tissue often occurs. Chronic exposure may inflame the skin or
8. HANDS/FEET ■ Elbow length PVC gloves. When handling corrosive liquids, wear trousers or overalls outside of boots, to avoid spills entering boots. Suitability and durability of glove type is dependent on usage. Important factors in the selection of gloves include: such as: frequency and duration of contact, chemical resistance of glove material, glove thickness and dexterity Select gloves tested to a relevant standard (e.g. Europe EN 374, US F739). When prolonged or frequently repeated contact may occur, a glove with a protection class of 5 or higher (breakthrough time greater than 240 minutes according to EN 374) is recommended. When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN 374) is recommended. Contaminated gloves should be replaced. Gloves must only be worn on clean hands. After using gloves, hands should be washed and dried thoroughly. Application of a non-perfumed moisturiser is recommended. Where hydrogen peroxide exposure may occur do NOT wear PVA gloves. DO NOT use leather or cotton gloves, leather shoes as spill may cause fire. Care: Effects may be delayed. Hand cream offers no protection for hydrogen peroxide and should not be used. OTHER ■ Overalls. PVC Apron. PVC protective suit may be required if exposure severe. Eyewash unit. Ensure there is ready access to a safety shower. Some plastic personal protective equipment (PPE) (e.g. gloves, aprons, overshoes) are not recommended as they may produce static electricity. For large scale or continuous use wear tight-weave non-static clothing (no metallic fasteners, cuffs or pockets), non sparking safety footwear. GLOVE SELECTION INDEX ■ Glove selection is based on a modified presentation of the: "Forsberg Clothing Performance Index". The effect(s) of the following substance(s) are taken into account in the computer-generated selection: hydrogen peroxide ■ Protective Material CPI *. NAT+NEOPR+NITRILE A NATURAL RUBBER A NATURAL+NEOPRENE A NEOPRENE A NEOPRENE/NATURAL A NITRILE A PVC A ■ * CPI - Chemwatch Performance Index A: Best Selection B: Satisfactory; may degrade after 4 hours continuous immersion C: Poor to Dangerous Choice for other than short term immersion NOTE: As a series of factors will influence the actual performance of the glove, a final selection must be based on detailed observation. - * Where the glove is to be used on a short term, casual or infrequent basis, factors such as "feel" or convenience (e.g. disposability), may dictate a choice of gloves which might otherwise be unsuitable following long-term or frequent use. A qualified practitioner should be consulted. RESPIRATOR ■ Selection of the Class and Type of respirator will depend upon the level of breathing zone contaminant and the chemical nature of the contaminant. Protection Factors (defined as the ratio of contaminant outside and inside the mask) may also be important. Breathing Zone Level ppm (volume) Maximum Protection Factor Half-face Respirator Full -Face Respirator 1000 10 B-1 - 1000 50 - B-1 5000 50 Airline* - 5000 100 - B-2 10000 100 - B-3 100+ Airline* * * - Continuous Flow ** - Continuous-flow or positive pressure demand. The local concentration of material, quantity and conditions of use determine the type of personal protective equipment required. Use appropriate NIOSH-certified respirator based on informed professional judgement. In conditions where no reasonable estimate of exposure can be made, assume the exposure is in a concentration IDLH and use NIOSH-certified full face pressure demand SCBA with a minimum service life of 30 minutes, or a combination full facepiece pressure demand SAR with auxiliary self-contained air supply. Respirators provided only for escape from IDLH atmospheres shall be NIOSH-certified for
9. escape from the atmosphere in which they will be used. ENGINEERING CONTROLS ■ Explosive reaction may result from the interaction of strong oxidizers and organics. Do NOT use strong oxidizing agents in fume hoods designed for other purposes. Identify fume hoods used for strong oxidizing agents with large warning signs. Provide exhaust ventilation and room supply air in accordance with appropriate Standard. Utilize local exhaust ventilation within the hood to minimize condensation of vapors inside the hood. Locate all utility controls outside the hood. Materials of construction for this type of hood and ductwork must be non-reactive, preferably acid resistant and relatively impervious. AVOID ORGANIC MATERIALS unless known to be safe. Stainless steel type 316 with welded joints is preferred. Unplasticized polyvinyl chloride or an inorganic ceramic coating such as porcelain is acceptable. Ease of cleanliness is paramount. Use stainless steel with accessible rounded corners and all -welded construction. The work surface should be water-tight with a minimum of 1 cm (1/2") dished front and sides and an integral trough at the rear to collect the washdown water. Design washdown facilities into the hood and ductwork. Use daily or more often to thoroughly clean water-soluble oxidizers from the exhaust system surfaces. Each hood should have an individual exhaust system. Slope horizontal runs to drain. Avoid sharp turns. Construct the hood and ductwork to allow easy visual inspection. Where required use a high efficiency (greater than 80%) wet collector constructed for water-soluble oxidizer service. Locate as close to the hood as possible to minimize the accumulation of the oxidizer in the exhaust duct. Use only a metallic fan protected by an inorganic coating (preferably acid-resistant), or an air ejector. Lubricate the fan with a fluorocarbon type grease. Locate the fan outside the building. The exhaust discharge must terminate out-of-doors preferably using a vertical discharge cap which extends well above the roof eddy zone. Air contaminants generated in the workplace possess varying "escape" velocities which, in turn, determine the "capture velocities" of fresh circulating air required to effectively remove the contaminant. Type of Determinant: Air Speed: solvent, vapors, degreasing etc., evaporating from tank (in still air). 0.25-0.5 m/s (50-100 f/min.) aerosols, fumes from pouring operations, intermittent container filling, low speed conveyer transfers, welding, spray drift, plating acid fumes, pickling (released at low velocity into zone of active generation) 0.5-1 m/s (100 -200 f/min.) direct spray, spray painting in shallow booths, drum filling, conveyer loading, crusher dusts, gas discharge (active generation into zone of rapid air motion) 1-2.5 m/s (200 -500 f/min.) grinding, abrasive blasting, tumbling, high speed wheel generated dusts (released at high initial velocity into zone of very high rapid air motion). 2.5-10 m/s (500 -2000 f/min.) Within each range the appropriate value depends on: Lower end of the range Upper end of the range 1: Room air currents minimal or favourable to capture 1: Disturbing room air currents 2: Contaminants of high toxicity 2: Contaminants of low toxicity or of nuisance value only. 3: Intermittent, low production. 3: High production, heavy use 4: Large hood or large air mass in motion 4: Small hood-local control only Simple theory shows that air velocity falls rapidly with distance away from the opening of a simple extraction pipe. Velocity generally decreases with the square of distance from the extraction point (in simple cases). Therefore the air speed at the extraction point should be adjusted, accordingly, after reference to distance from the contaminating source. The air velocity at the extraction fan, for example, should be a minimum of 1-2 m/s (200 -400 f/min.) for extraction of solvents generated in a tank 2 meters distant from the extraction point. Other mechanical considerations, producing performance deficits within the extraction apparatus, make it essential that theoretical air velocities are multiplied by factors of 10 or more when extraction systems are installed or used. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES PHYSICAL PROPERTIES Liquid. Mixes with water. Corrosive. State Liquid Molecular Weight 34.02 as H2O2 Melting Range (°F) 31.28 Viscosity Not Available Boiling Range (°F) 302.36 Solubility in water (g/L) Miscible Flash Point (°F) Not applicable pH (1% solution) Not available. Decomposition Temp (°F) Not applicable pH (as supplied) Not applicable Autoignition Temp (°F) Not applicable Vapor Pressure (mmHg) 5.025 @ 30C Upper Explosive Limit (%) Not applicable Specific Gravity (water=1) 1.40 @ 25C Lower Explosive Limit (%) Not applicable Relative Vapor Density (air=1) Not available. Volatile Component (%vol) Not available. Evaporation Rate Not available APPEARANCE Clear, colourless to light blue, water-like liquid, odourless (or with a characteristic slightly acidic odour). Pure hydrogen
13. DOT: Symbols: None Hazard class or Division: 5.1 Identification Numbers: UN2015 PG: I Label Codes: 5.1, 8 Special provisions: 12, B53, B80, B81, B85, T9, TP2, TP6, TP24, TP37 Packaging: Exceptions: None Packaging: Non-bulk: 201 Packaging: Exceptions: None Quantity limitations: Passenger aircraft/rail: Forbidden Quantity Limitations: Cargo aircraft only: Forbidden Vessel stowage: Location: D Vessel stowage: Other: 25, 66, 75. Hazardous materials descriptions and proper shipping names: Hydrogen peroxide, stabilized or Hydrogen peroxide aqueous solutions, stabilized with more than 60 percent hydrogen peroxide Air Transport IATA: ICAO/IATA Class: 5.1 (8) ICAO/IATA Subrisk: None UN/ID Number: 2015 Packing Group: - Special provisions: None Cargo Only Packing Instructions: Forbidden Maximum Qty/Pack: Forbidden Passenger and Cargo Passenger and Cargo Packing Instructions: Forbidden Maximum Qty/Pack: Forbidden Passenger and Cargo Limited Quantity Passenger and Cargo Limited Quantity Packing Instructions: - Maximum Qty/Pack: - Shipping Name: HYDROGEN PEROXIDE, AQUEOUS SOLUTION, STABILIZED Maritime Transport IMDG: IMDG Class: 5.1 IMDG Subrisk: 8 UN Number: 2015 Packing Group: I EMS Number: F-H,S-Q Special provisions: None Limited Quantities: None Shipping Name: HYDROGEN PEROXIDE, STABILIZED or HYDROGEN PEROXIDE, AQUEOUS SOLUTION, STABILIZED with more than 60% hydrogen peroxide Section 15 - REGULATORY INFORMATION hydrogen peroxide (CAS: 7722-84-1) is found on the following regulatory lists; "Canada - Alberta Occupational Exposure Limits","Canada - British Columbia Occupational Exposure Limits","Canada - Northwest Territories Occupational Exposure Limits (English)","Canada - Nova Scotia Occupational Exposure Limits","Canada - Ontario Occupational Exposure Limits","Canada - Prince Edward Island Occupational Exposure Limits","Canada - Quebec Permissible Exposure Values for Airborne Contaminants (English)","Canada - Saskatchewan Industrial Hazardous Substances","Canada - Saskatchewan Occupational Health and Safety Regulations - Contamination Limits","Canada - Yukon Permissible Concentrations for Airborne Contaminant Substances","Canada Ingredient Disclosure List (SOR/88-64)","Canada Toxicological Index Service - Workplace Hazardous Materials Information System - WHMIS (English)","Canada Toxicological Index Service - Workplace Hazardous Materials Information System - WHMIS (French)","GESAMP/EHS Composite List - GESAMP Hazard Profiles","IMO IBC Code Chapter 17: Summary of minimum requirements","IMO MARPOL 73/78 (Annex II) - List of Noxious Liquid Substances Carried in Bulk","International Agency for Research on Cancer (IARC) - Agents Reviewed by the IARC Monographs","International Air Transport Association (IATA) Dangerous Goods Regulations","OECD Representative List of High Production Volume (HPV) Chemicals","US - Alaska Limits for Air Contaminants","US - California Occupational Safety and Health Regulations (CAL/OSHA) - Hazardous Substances List","US - California Permissible Exposure Limits for Chemical Contaminants","US - Connecticut Hazardous Air Pollutants","US - Hawaii Air Contaminant Limits","US - Massachusetts Oil & Hazardous Material List","US - Michigan Exposure Limits for Air Contaminants","US - Minnesota Hazardous Substance List","US - Minnesota Permissible Exposure Limits (PELs)","US - New Jersey Right to Know Hazardous Substances","US - Oregon Hazardous Materials","US - Oregon Permissible Exposure Limits (Z1)","US - Pennsylvania - Hazardous Substance List","US - Rhode Island Hazardous Substance List","US - Tennessee Occupational Exposure Limits - Limits For Air Contaminants","US - Vermont Permissible Exposure Limits Table Z -1-A Final Rule Limits for Air Contaminants","US - Vermont Permissible Exposure Limits Table Z -1-A Transitional Limits for Air Contaminants","US - Washington Permissible exposure limits of air contaminants","US - Wyoming List of Highly Hazardous Chemicals, Toxics and Reactives","US - Wyoming Toxic and Hazardous Substances Table Z1 Limits for Air Contaminants","US ACGIH Threshold Limit Values (TLV)","US ACGIH Threshold Limit Values (TLV) - Carcinogens","US Department of Homeland Security Chemical Facility Anti-Terrorism Standards - Chemicals of Interest","US DOE Temporary Emergency Exposure Limits (TEELs)","US EPA Master Testing List - Index I Chemicals Listed","US FDA Indirect Food Additives: Adhesives and Components of Coatings - Substances for Use Only as Components of Adhesives - Adhesives","US Food Additive Database","US Inventory of Effective Food Contact Substance Notifications","US List of Lists - Consolidated List of Chemicals Subject to the Emergency Planning and Community Right-to-Know Act (EPCRA) and Section 112(r) of the Clean Air Act","US NFPA 1 Annex B Typical Oxydizers","US NIOSH Recommended Exposure Limits (RELs)","US OSHA List of Highly Hazardous Chemicals, Toxics and Reactives","US OSHA Permissible Exposure Levels (PELs) - Table Z1","US SARA Section 302 Extremely Hazardous Substances","US Toxic Substances Control Act (TSCA) - Inventory","USA: Chemical Facility Anti-Terrorism Standards - List Appendix A - 6CFR 27" Regulations for ingredients water (CAS: 7732-18-5) is found on the following regulatory lists;
6. Section 7 - HANDLING AND STORAGE PROCEDURE FOR HANDLING ■ DO NOT allow clothing wet with material to stay in contact with skin Avoid personal contact and inhalation of dust, mist or vapors. Provide adequate ventilation. Always wear protective equipment and wash off any spillage from clothing. Keep material away from light, heat, flammables or combustibles. Keep cool, dry and away from incompatible materials. Avoid physical damage to containers. DO NOT repack or return unused portions to original containers. Withdraw only sufficient amounts for immediate use. Contamination can lead to decomposition leading to possible intense heat and fire. When handling NEVER smoke, eat or drink. Always wash hands with soap and water after handling. Use only good occupational work practice. Observe manufacturer's storing and handling directions. RECOMMENDED STORAGE METHODS ■ Glass container. All inner and sole packagings for substances in Packing Group I,must be hermetically sealed. Hydrogen peroxide containing/ generating materials requiring rigid packaging. Store in: containers with vented lids. properly passivated aluminium containers. properly passivated stainless steel. polyethylene containers. porcelain, vitreous stoneware Teflon lined containers. STORAGE REQUIREMENTS ■ In addition, Goods of Class 5.1, packing group I should be: stored in a room or space with free vents stored in piles so that (i) the length of the pile does not exceed 3 metres; (ii) the height of the pile does not exceed 3 metres if the area is provided with automatic fire extinguishers or 1.2 metres if not. stored in a room that is equipped with an automatic fire sprinkler capable of a discharge rate of at least 10 litres per minute per square meter of floor area, where 1000 kgs or more of the material is to be stored. SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS X X X X X 0 X: Must not be stored together O: May be stored together with specific preventions +: May be stored together Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION EXPOSURE CONTROLS Source Material TWA ppm TWA mg/m ³ STEL ppm STEL mg/m ³ Peak ppm Peak mg/m ³ TWA F/CC Notes Canada - Alberta Occupational Exposure Limits hydrogen peroxide (Hydrogen peroxide) 1 1.4 Canada - British Columbia Occupational Exposure Limits hydrogen peroxide (Hydrogen peroxide) 1 US NIOSH Recommended Exposure Limits (RELs) hydrogen peroxide (Hydrogen peroxide) 1 1.4 US OSHA Permissible Exposure Levels (PELs) - Table Z1 hydrogen peroxide (Hydrogen peroxide) 1 1.4 US ACGIH Threshold Limit Values (TLV) hydrogen peroxide (Hydrogen peroxide) 1 TLV Basis: eye, upper respiratory tract & skin irritation Canada - Ontario Occupational Exposure Limits hydrogen peroxide (Hydrogen peroxide) 1 1.4 US - Vermont Permissible Exposure Limits Table Z -1-A Transitional Limits for Air Contaminants hydrogen peroxide (Hydrogen peroxide) 1 1.4
7. US - Vermont Permissible Exposure Limits Table Z -1-A Final Rule Limits for Air Contaminants hydrogen peroxide (Hydrogen peroxide) 1 1.4 US - Tennessee Occupational Exposure Limits - Limits For Air Contaminants hydrogen peroxide (Hydrogen peroxide) 1 1.4 US - Minnesota Permissible Exposure Limits (PELs) hydrogen peroxide (Hydrogen peroxide) 1 1.4 US - California Permissible Exposure Limits for Chemical Contaminants hydrogen peroxide (Hydrogen peroxide, as H2O2) 1 1.4 Canada - Quebec Permissible Exposure Values for Airborne Contaminants (English) hydrogen peroxide (Hydrogen peroxide) 1 1.4 US - Hawaii Air Contaminant Limits hydrogen peroxide (Hydrogen peroxide) 1 1.4 2 3 US - Alaska Limits for Air Contaminants hydrogen peroxide (Hydrogen peroxide) 1 1.4 Canada - Saskatchewan Occupational Health and Safety Regulations - Contamination Limits hydrogen peroxide (Hydrogen peroxide) 1 2 Canada - Yukon Permissible Concentrations for Airborne Contaminant Substances hydrogen peroxide (Hydrogen peroxide) 1 1.5 2 2.8 US - Washington Permissible exposure limits of air contaminants hydrogen peroxide (Hydrogen peroxide) 1 3 US - Michigan Exposure Limits for Air Contaminants hydrogen peroxide (Hydrogen peroxide) 1 1.4 Canada - Prince Edward Island Occupational Exposure Limits hydrogen peroxide (Hydrogen peroxide) 1 TLV Basis: eye, upper respiratory tract & skin irritation US - Wyoming Toxic and Hazardous Substances Table Z1 Limits for Air Contaminants hydrogen peroxide (Hydrogen peroxide) 1 1.4 Canada - Nova Scotia Occupational Exposure Limits hydrogen peroxide (Hydrogen peroxide) 1 TLV Basis: eye, upper respiratory tract & skin irritation US - Oregon Permissible Exposure Limits (Z1) hydrogen peroxide (Hydrogen peroxide) 1 1.4 Canada - Northwest Territories Occupational Exposure Limits (English) hydrogen peroxide (Hydrogen peroxide) 1 1.4 2 2.8 The following materials had no OELs on our records • water: CAS:7732-18 -5 EMERGENCY EXPOSURE LIMITS Material Revised IDLH Value (mg/m3) Revised IDLH Value (ppm) hydrogen peroxide 75 [Unch] MATERIAL DATA HYDROGEN PEROXIDE: ■ for hydrogen peroxide NOTE: Detector tubes for hydrogen peroxide, measuring in excess of 0.1 ppm, are available commercially. Exposure at or below the TLV-TWA is thought to minimise irritation and bleaching of hair. WATER: ■ No exposure limits set by NOHSC or ACGIH. PERSONAL PROTECTION Consult your EHS staff for recommendations EYE ■ Chemical goggles. Full face shield. Contact lenses pose a special hazard; soft contact lenses may absorb irritants and all lenses concentrate them.
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